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        基于靜電紡絲技術的農藥傳遞體系的制備與性能表征
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        1.鹽城工學院 紡織服裝學院;2.南京高正農用化工有限公司;3.鹽城市權航科技有限公司

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        中圖分類號:

        TQ 450.6;TB 332

        基金項目:

        江蘇省農業科技自主創新資金項目(CX(21)3086);國家自然科學基金青年項目(52103067);江蘇省高等學校大學生創新創業訓練計劃項目(2022103050062);鹽城工學院校級科研資助項目(xjr2020042);鹽城工學院產學研合作項目(2022040414)


        Preparation and characterization of pesticide delivery system based on electrospinning
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        1.College of Textile & Cloting,Yancheng Institute of Technology,Yancheng;2.Nanjing Gaozheng agrochemical Co,Ltd,Nanjing;3.Yancheng Quanhang Technology Co,Ltd,Yancheng

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          摘要:

          為獲得一種新型高載藥量、易分散型農藥制劑,基于藥物傳遞理論,以阿維菌素(AVM)為農藥模型,以乙基纖維素(EC)為主要農藥載體,以卡波姆(CB)為改性材料,利用靜電紡納米纖維載藥技術構建一種具有微納結構的農藥傳遞體系。通過對復配比例、溶解參數及紡絲條件的探索,結果表明:采用N,N-二甲基乙酰胺與乙醇以體積比3∶1的混合溶劑對載體材料EC與CB分別進行溶解,EC與CB紡絲液的體積復配比為1∶1時,農藥傳遞體系的載藥量可高達35.7%,包封率接近100%,耐光解性大幅提升。并且,該農藥傳遞體系的水分散性非常優異,具有長效釋藥性。

          Abstract:

          In order to obtain a new pesticide formulation with high drug loading and good dispersion property, based on drug delivery theory, a pesticide delivery system (PDS) with a special micro/nano composite structure was constructed by electrospinning technology with avermectin (AVM) as the pesticide model, ethyl cellulose (EC) as the main pesticide carrier, and carbomer (CB) as the modified material. Through the exploration of compound proportion, dissolution parameters and spinning conditions, the results show that: The mixed solvent of N, N-dimethylacetamide and ethanol was used to dissolve the carrier material EC and CB. When the volume complex ratio of EC and CB spinning solution was 1:1, the loading rate of AVM in PDS was up to 35.7%, the encapsulation rate of AVM in PDS was close to 100%, and the photolysis resistance was greatly improved. Besides, this PDS has excellent property of water dispersion, long duration of efficacy.

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        吳煥嶺,裔士釗,謝周良,冒海燕,汪茂勤,康正芳.基于靜電紡絲技術的農藥傳遞體系的制備與性能表征[J].精細化工,2023,40(8):

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        歷史
        • 收稿日期:2022-10-25
        • 最后修改日期:2023-01-03
        • 錄用日期:2023-01-06
        • 在線發布日期: 2023-06-12
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